Localized provoked vulvodynia is a term used to describe vulvodynia that affects only a small part of the vulva and only hurts when the area is touched. The most common location for localized provoked vulvodynia is at the opening to the vagina (called the vestibule). When vulvodynia affects the vestibule it is called vestibulodynia or Vulvar Vestibulitis Syndrome(VVS). These women typically complain of pain during intercourse or with the insertion of tampons, wearing tight jeans, riding a bicycle, etc. It occurs in women of all ages. Some women have had vestibulodynia (VVS) since they first used tampons or from their first intercourse. Other women have had painless tampon insertion or intercourse in the past and the pain develops at a later time. It is estimated that about 15% of women will have some sort of vulvar pain in their lifetime. Typically, these women have seen a number of health care practitioners and have had numerous attempts at therapy with topical or oral antifungals, topical steroids and antibiotics. Often, these provide no long-term relief.