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Vulvar Vestibulitis Syndrome (VVS)

 

Which antiseizure medications are used to treat vestibulodynia (VVS)?


Antiseizure medications have been used for the treatment of many chronic pain conditions of nerve origin. Not all antiseizure medications can be used to treat vestibulodynia (VVS). The antiseizure medications most commonly used for vestibulodynia (VVS) include Gabapentin (Neurontin) and carbamazepine (Tegretol). Pregabalin (Lyrica) is a newer drug very similar to gabapentin but with possibly fewer side effects. However there is no generic version of pregabalin. Topiramate (Topamax) and oxcarbazepine (Trileptal) are also antiseizure medications that may also be used for treating vestibulodynia (VVS). Gabapentin tends to have fewer side effects than the tricyclic antidepressants. The side effects of gabapentin include sleepiness and dizziness and, less commonly, gastrointestinal symptoms and mild leg swelling. Gabapentin can cause or increase balance problems in older women, and may have a mild affect in causing them not to think clearly. For patients with kidney problems the dose should be adjusted carefully. It may take 3 to 8 weeks for gabapentin to become effective for pain control.